Hydantoin derivatives for the treatment of inflammatory disorders

This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.

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Bibliographic Details
Main Authors SEONG-HEON KIM, LEI CHEN, WENSHENG YU, MICHAEL K.C. WONG, JANETA POPOVICI-MULLER, RAZIA RIZVI, BRIAN J. LAVEY, GUOWEI ZHOU, CHAOYANG DAI, DANSU LI, BANDARPALLE B. SHANKAR, DE-YI YANG, VINAY M. GIRIJAVALLABHAN, KRISTIN E. ROSNER, M. ARSHAD SIDDIQUI, NENG-YANG SHIH, ROBERT FELTZ, JOSEPH A. KOZLOWSKI, LING TONG
Format Patent
LanguageEnglish
Published 26.07.2007
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.
Bibliography:Application Number: AU20070207707