Bis-aryl kinase inhibitors and their use in the treatment of inflammation, angiogenesis and cancer

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and...

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Main Authors PATEL, VINOD F, BELLON, STEVEN, LEE, MATTHEW, GERMAIN, JULIE, KIM, JOSEPH L, FELLOWS, INGRID M, HARVEY, TIMOTHY S, HARMANGE, JEANRISTOPHE, KIM, TAE-SEONG, TASKER, ANDREW, D'ANGELO, NOEL, BOOKER, SHON, DOMINGUEZ, CELIA, LIU, LONGBIN
Format Patent
LanguageEnglish
Published 03.05.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Bibliography:Application Number: AU20060265835