Inhibitors of checkpoint kinases

The instant invention provides for compounds which comprise substituted pyridyl aminothiazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of t...

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Bibliographic Details
Main Authors JACOB M. HOFFMAN, CHENG WANG, MARK E. FRALEY, CONSTANTINE KREATSOULAS, VADIM Y. DUDKIN, KENNETH L. ARRINGTON
Format Patent
LanguageEnglish
Published 21.12.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The instant invention provides for compounds which comprise substituted pyridyl aminothiazoles that inhibit CHK1 activity. The invention also provides for compositions comprising such inhibitory compounds and methods of inhibiting CHK1 activity by administering the compound to a patient in need of treatment of cancer.
Bibliography:Application Number: AU20060258101