4- (2, 6-dichlorobenzoylamino) -lH-pyrazole-3 -carboxylic acid piperidin- 4 -ylamid acid addition salts as kinase inhibitors

The invention provides an acid addition salt of 4-(2,6-dichloro-benzoylamino)-lH- pyrazole-3-carboxylic acid piperidin-4-ylamide and crystals thereof, the salt being formed with an acid selected from methanesulphonic acid and acetic acid and mixtures thereof. Also provided are the novel uses of salt...

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Bibliographic Details
Main Authors REES, DAVID CHARLES, TREWARTHA, GARY, WYATT, PAUL GRAHAM, VINKOVIC, MLADEN
Format Patent
LanguageEnglish
Published 07.06.2012
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention provides an acid addition salt of 4-(2,6-dichloro-benzoylamino)-lH- pyrazole-3-carboxylic acid piperidin-4-ylamide and crystals thereof, the salt being formed with an acid selected from methanesulphonic acid and acetic acid and mixtures thereof. Also provided are the novel uses of salts of 4-(2,6-dichloro-benzoylamino)-lH- pyrazole-3-carboxylic acid piperidin-4-ylamide, processes for the preparation of 4- (2,6-dichloro-benzoylamino)-lH-pyrazole-3-carboxylic acid piperidin-4-ylamide and its salts and novel chemical intermediates.
Bibliography:Application Number: AU20060207323