Stable pharmaceutical compositions of platinum (II) antitumour agents

A pharmaceutical composition comprising a platinum (II) complex compound in n aqueous solvent. The pharmaceutical composition is prepared by the essential steps of: (i) adding a platinum (II) complex compound to an oxygen enriched aqueous solvent to obtain a solution; (ii) Sterilizing the solution (...

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Main Authors MANOJ KUMAR PANANCHUKUNNATH, RAMA MUKHERJEE, DINESH KUMAR, SATISH CHANDRA UPADHYAY, AJEET KUMAR SINGH, ANAND C. BURMAN
Format Patent
LanguageEnglish
Published 05.10.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A pharmaceutical composition comprising a platinum (II) complex compound in n aqueous solvent. The pharmaceutical composition is prepared by the essential steps of: (i) adding a platinum (II) complex compound to an oxygen enriched aqueous solvent to obtain a solution; (ii) Sterilizing the solution (iii) Filling the sterilizedsolution of step (ii) into suitable containers; and (iv) Sealing the containers. The oxygen enriched aqueous solvent is obtained by purging or bubbling of a gas into an aqueous solvent for 30 to 150 minutes. A device for preparing the pharmaceutical composition is illustrated in FIG. 1. The composition is used for treatment of a human or an animal cancerous disease by the administration of pharmaceutical compositions of platinum (II) complex compounds as per the claim 1, to the human or animal in need of said treatment.
Bibliography:Application Number: AU20050329764