Compounds and methods of use thereof

Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.

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Bibliographic Details
Main Authors SIMON, N. HAYDAR, MICHAEL L. JONES, TATYANA DYAKONOV, CHRISTOPHER J. MARKWORTH, JAMES F. BURNS, DAVID N. VANVLIET, JESSYMOL MATHEW, JOHN R. DIDSBURY, GLENN C. COLLUPY, LEONARD A. CABANA, FRANK J. SCHOENEN, DAVID N. MIDDLEMISS, FRANCINE F. LI
Format Patent
LanguageEnglish
Published 11.05.2006
Subjects
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Imidazole and benzimidazole boronic acid compounds, analogs thereof, and pharmaceutical formulations are described, along with methods of use thereof for inhibiting inflammatory cytokines such as tumor necrosis factor alpha (TNF-alpha) in a subject in need thereof.
Bibliography:Application Number: AU20050302519