Improved cytokine design

The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins...

Full description

Saved in:
Bibliographic Details
Main Authors EVA E. SZEGEZDI, LUIS SERRANO, GREGORIO FERNANDEZ-BALLESTER, VICENTE R. TUR, ALBERT MARTINUS VAN DER SLOOT, WILHELMUS J. QUAX, AFSHIN SAMALI, ROBERT H. COOL, MARGARET M. MULLALLY
Format Patent
LanguageEnglish
Published 23.06.2005
Subjects
CHEMISTRY
INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
Online AccessGet full text

Cover

More Information
Summary:The present invention relates to novel methods for the design of proteins, in particular, cytokines. These methods allow the stabilisation of such cytokines, as well as modification of their selectivity/specificity for their cognate receptors. The invention also relates to various modified proteins that have been designed by the methods of the invention.
Bibliography:Application Number: AU20040297039