Pyridyl derivatives and their use as therapeutic agents

Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I): wherein x, y, W, V, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 7a , R 8 , R 8a , R 9 , R 9a , R 10 and R 10a are defined herein. Pharmaceutical compo...

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Main Authors VANDNA RAINA, CHI TU, MELWYN ABREO, MICHAEL D. WINTHER, MIKHAIL A. KONDRATENKO, RAJENDER KAMBOJ, MEHRAN SEID BAGHERZADEH, SHIFENG LIU, HEINZ W. GSCHWEND, SERGUEI SVIRIDOV, CINDY J. HUDSON, ZAIHUI ZHANG, VISHNUMURTHY KODUMURU, WENBAO LI, SHAOYI SUN, DANIEL F. HARVEY
Format Patent
LanguageEnglish
Published 09.04.2009
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Abstract Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I): wherein x, y, W, V, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 7a , R 8 , R 8a , R 9 , R 9a , R 10 and R 10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
AbstractList Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I): wherein x, y, W, V, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 7a , R 8 , R 8a , R 9 , R 9a , R 10 and R 10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Author SHAOYI SUN
SHIFENG LIU
MIKHAIL A. KONDRATENKO
MELWYN ABREO
DANIEL F. HARVEY
RAJENDER KAMBOJ
HEINZ W. GSCHWEND
CHI TU
CINDY J. HUDSON
ZAIHUI ZHANG
VANDNA RAINA
SERGUEI SVIRIDOV
WENBAO LI
MEHRAN SEID BAGHERZADEH
VISHNUMURTHY KODUMURU
MICHAEL D. WINTHER
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– fullname: SHIFENG LIU
– fullname: HEINZ W. GSCHWEND
– fullname: SERGUEI SVIRIDOV
– fullname: CINDY J. HUDSON
– fullname: ZAIHUI ZHANG
– fullname: VISHNUMURTHY KODUMURU
– fullname: WENBAO LI
– fullname: SHAOYI SUN
– fullname: DANIEL F. HARVEY
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Snippet Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I): wherein...
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SubjectTerms CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Title Pyridyl derivatives and their use as therapeutic agents
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