Pyridyl derivatives and their use as therapeutic agents

Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I): wherein x, y, W, V, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 7a , R 8 , R 8a , R 9 , R 9a , R 10 and R 10a are defined herein. Pharmaceutical compo...

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Main Authors VANDNA RAINA, CHI TU, MELWYN ABREO, MICHAEL D. WINTHER, MIKHAIL A. KONDRATENKO, RAJENDER KAMBOJ, MEHRAN SEID BAGHERZADEH, SHIFENG LIU, HEINZ W. GSCHWEND, SERGUEI SVIRIDOV, CINDY J. HUDSON, ZAIHUI ZHANG, VISHNUMURTHY KODUMURU, WENBAO LI, SHAOYI SUN, DANIEL F. HARVEY
Format Patent
LanguageEnglish
Published 09.04.2009
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Compounds for treating an SCD-mediated disease or condition in a mammal, preferably a human, are disclosed, wherein the compounds are of formula (I): wherein x, y, W, V, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 7a , R 8 , R 8a , R 9 , R 9a , R 10 and R 10a are defined herein. Pharmaceutical compositions comprising the compounds of formula (I) are also disclosed.
Bibliography:Application Number: AU20040261267