Safe chemical uncouplers for the treatment of obesity

This invention relates to chemical uncouplers with a broader safety window making the use of them in treating obesity and, consequently, in the treatment of obesity related diseases and conditions such as atherosclerosis, hypertension, diabetes, especially type 2 diabetes (NIDDM (non-insulin depende...

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Main Authors THOMAS KRUSE HANSEN, BIRGIT SEHESTED HANSEN, SOREN TULLIN, MORTEN COLDING-JORGENSEN
Format Patent
LanguageEnglish
Published 07.06.2004
Edition7
Subjects
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Summary:This invention relates to chemical uncouplers with a broader safety window making the use of them in treating obesity and, consequently, in the treatment of obesity related diseases and conditions such as atherosclerosis, hypertension, diabetes, especially type 2 diabetes (NIDDM (non-insulin dependent diabetes mellitus)), impaired glucose tolerance, dyslipidemia, coronary heart disease, gallbladder disease, osteoarthritis and various types of cancer such as endometrial, breast, prostate and colon cancers and the risk for premature death as well as other conditions, such as diseases and disorders, which conditions are improved by an increase in mitochondrial respiration, more attractive.
Bibliography:Application Number: AU20030275939