Cyclohexyl sulphones as gamma-secretase inhibitors

Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.

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Bibliographic Details
Main Authors SUSANNAH WILLIAMS, JOANNE THOMSON, ANDREW PATE OWENS, ALAN JOHN NADIN, DUNCAN EDWARD SHAW, IAN CHURCHER, TIMOTHY HARRISON, SONIA KERRAD
Format Patent
LanguageEnglish
Published 15.10.2009
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Compounds of formula I: inhibit the processing of APP by gamma-secretase, and hence are useful in treating or preventing Alzheimer's disease.
Bibliography:Application Number: AU20030269211