Nucleic acid molecule encoding an allergen preprotein of a mite of genus dermatophagoides or euroglyphus and use thereof for protecting said allergen in plants

The invention concerns a purified nucleic acid molecule comprising or consisting of a polynucleotide sequence coding for (i) the mature form of a protein allergen of a mite of genus Dermatophagoides and (ii) a propeptide located at the N-terminal end of said protein allergen. Said nucleotide sequenc...

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Bibliographic Details
Main Authors LOIC FAYE, VERONIQUE GOMORD, DAVID LIENARD, ERICA VAN OORT, ALAIN DIDIER LAURENT, FRANCOIS DORLHAC DE BORNE, RONALD VAN REE
Format Patent
LanguageEnglish
Published 23.01.2004
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention concerns a purified nucleic acid molecule comprising or consisting of a polynucleotide sequence coding for (i) the mature form of a protein allergen of a mite of genus Dermatophagoides and (ii) a propeptide located at the N-terminal end of said protein allergen. Said nucleotide sequence also codes for (iii) a signal peptide located at the N-terminal end of said propeptide. The invention also concerns the use of said nucleic acid molecule for preparing recombinant allergens. The invention further concerns the method for obtaining said allergen.
Bibliography:Application Number: AU20030269011