NOVEL Nogo RECEPTOR-LIKE POLYPEPTIDE AND DNA THEREOF

A novel Nogo receptor-like polypeptide is found out as a protein showing elevated expression in the skeletal muscle of a Zucker fatty rat, which is a diabetes model rat, having a restricted diet and taking exercises. Moreover, a human homolog protein corresponding to it is found out. The above polyp...

Full description

Saved in:
Bibliographic Details
Main Authors SATOSHI ORITA, ATSUYUKI SHIMAZAKI, TORU YANAGIMOTO, TAKEO OSHIMA, MASATOSHI NAKAJIMA
Format Patent
LanguageEnglish
Published 23.01.2004
Edition7
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
Online AccessGet full text

Cover

More Information
Summary:A novel Nogo receptor-like polypeptide is found out as a protein showing elevated expression in the skeletal muscle of a Zucker fatty rat, which is a diabetes model rat, having a restricted diet and taking exercises. Moreover, a human homolog protein corresponding to it is found out. The above polypeptide is useful as a diabetic marker and a remedy for diabetes. Since this polypeptide is expressed most strongly in the cerebral cortex in the brain, it is also useful as a marker for neurodegenerative diseases such as Alzheimer's disease and a remedy for neurodegenerative diseases.
Bibliography:Application Number: AU20030246254