Vaccine formulation potentiated by the combination of a DNA and an antigen

The invention relates to a vaccine antigen formulation containing the following main components: a-) one or more DNAs that express one or more proteins in the immunized individual and b-) a viral antigen, in suitable proportions. The novelty of the invention lies in the potentiating effect exerted b...

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Main Authors JULIO C. ALVAREZ OBREGON, ALEXIS MUSACCHIO LASA, ROLANDO PAJON FEYT, SANTIAGO DUENAS CARRERA, NELSON ACOSTA RIVERO, JUAN MORALES GRILLO, ARIEL VINA RODRIGUEZ, LIZ ALVAREZ-LAJONCHERE PONCE DE LEON, GILLIAN MARTINEZ DONATO
Format Patent
LanguageEnglish
Published 17.08.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention relates to a vaccine antigen formulation containing the following main components: a-) one or more DNAs that express one or more proteins in the immunized individual and b-) a viral antigen, in suitable proportions. The novelty of the invention lies in the potentiating effect exerted by at least one of the components on the immune response generated against the other. The invention also relates to the development of novel formulations, that minimize the number of components that can amplified and potentiate the range of immune response against different pathogenic entities. Said formulation are suitable for use in the pharmaceutical industry for prophylactic and/or therapeutic purposes in individuals.
Bibliography:Application Number: AU20020325783