Amphiphilic lipid nanoparticles for peptide and/or protein incorporation

Lipid nanoparticles loaded with drugs, such as peptides or proteins, are herein described. A process for obtaining them as well as their use for the preparation of a pharmaceutical composition is also disclosed. According to a preferred embodiment, the drug is a LHRH analogue, more preferably a LHRH...

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Bibliographic Details
Main Authors PIERANDREA ESPOSITO, DANIELA CHICCO, MARIA DORLY DEL CURTO
Format Patent
LanguageEnglish
Published 08.06.2006
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Lipid nanoparticles loaded with drugs, such as peptides or proteins, are herein described. A process for obtaining them as well as their use for the preparation of a pharmaceutical composition is also disclosed. According to a preferred embodiment, the drug is a LHRH analogue, more preferably a LHRH antagonist, and the lipid matrix comprises at least 70% w/w of monoglycerides.
Bibliography:Application Number: AU20020226374