Agents

Agents for stabilizing natural or backbone modified DNA and RNA triplexes and hybrids thereof by partly intercalative, partly non-intercalative binding wherein the agent is a compound of fomula (I) wherein n = 2 or 3 and x is 1 or 2. Use of the ligands as antigene/antisense enhancing agents and in p...

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Bibliographic Details
Main Authors BENGT NORDEN, JAN BERGMAN, HANS VALLBERG, ULRICA SEHLSTEDT, PALOK AICH, ASTRID GRASLUND
Format Patent
LanguageEnglish
Published 05.07.1999
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Agents for stabilizing natural or backbone modified DNA and RNA triplexes and hybrids thereof by partly intercalative, partly non-intercalative binding wherein the agent is a compound of fomula (I) wherein n = 2 or 3 and x is 1 or 2. Use of the ligands as antigene/antisense enhancing agents and in preparing drugs for treating retroviral infections are also described.
Bibliography:Application Number: AU1899099