Method of prognosis and diagnosis of congestive heart failure

Method of diagnosis or prognosis of heart failure or heart insufficiency and, if appropriate, the need of a prophylactic treatment, comprising the step of determining the amount of relaxin peptides or fragments or isoforms thereof in a sample of a body fluid such as blood serum or blood plasma, pref...

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Main Authors FRANZ PAUL ARMBRUSTER, THOMAS DSCHIETZIG, HANS-JURGEN GRON, KARL STANGL
Format Patent
LanguageEnglish
Published 27.05.2002
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
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Abstract Method of diagnosis or prognosis of heart failure or heart insufficiency and, if appropriate, the need of a prophylactic treatment, comprising the step of determining the amount of relaxin peptides or fragments or isoforms thereof in a sample of a body fluid such as blood serum or blood plasma, preferably by using polyclonal or monoclonal antibodies which bind peptides or fragments or isoforms of relaxin. Relaxin relaxin peptides or fragments or isoforms thereof can also be used for preparing a medicament for treatment or prophylactic treatment of congestive heart failure, for inhibition and modulating the effect of endothelin-1 and angiotensinll and also for prophylactic treatment of heart failure.
AbstractList Method of diagnosis or prognosis of heart failure or heart insufficiency and, if appropriate, the need of a prophylactic treatment, comprising the step of determining the amount of relaxin peptides or fragments or isoforms thereof in a sample of a body fluid such as blood serum or blood plasma, preferably by using polyclonal or monoclonal antibodies which bind peptides or fragments or isoforms of relaxin. Relaxin relaxin peptides or fragments or isoforms thereof can also be used for preparing a medicament for treatment or prophylactic treatment of congestive heart failure, for inhibition and modulating the effect of endothelin-1 and angiotensinll and also for prophylactic treatment of heart failure.
Author KARL STANGL
FRANZ PAUL ARMBRUSTER
THOMAS DSCHIETZIG
HANS-JURGEN GRON
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SubjectTerms CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
TESTING
Title Method of prognosis and diagnosis of congestive heart failure
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