(CARBOXYL)ALKYLOXYALKYL DERIVATIVES OF CYCLODEXTRINS

Clyclodextrin ethers or mixed ethers wherein one or several hydroxy groups of the cyclodextrin moiety are etherified with mono- or dihydroxyalkyl and in the case of mixed ethers, one or more of the remaining hydroxy groups of the cyclodextrin moiety are further etherified with (carboxyl)alkyl or (de...

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Bibliographic Details
Main Authors LASZLO JICSINSZKY, JOZSEF SZEJTLI
Format Patent
LanguageEnglish
Published 15.09.1992
Edition5
Subjects
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Summary:Clyclodextrin ethers or mixed ethers wherein one or several hydroxy groups of the cyclodextrin moiety are etherified with mono- or dihydroxyalkyl and in the case of mixed ethers, one or more of the remaining hydroxy groups of the cyclodextrin moiety are further etherified with (carboxyl)alkyl or (derivatized carboxyl)alkyl, and wherein one or more of the hydroxy groups of said mono- or dihydroxyalkyl groups are further etherified with (carboxyl)alkyl or (derivatized carboxyl) alkyl; the alkylcarbonylated derivatives thereof; the non-toxic metal and amine salt forms thereof; and the stereochemically isomeric forms thereof. Process for preparing said cyclodextrin derivatives. Cyclodextrin derivatives obtainable by said process. Complexes and pharmaceutical compositions comprising said cyclodextrin derivatives.
Bibliography:Application Number: AU1192092