PARENTERAL SOLUTION

Parenteral solutions comprising (a) a sparingly soluble medicament active compound, (b) a solvent consisting of (i) 5-100 M/V % of an organic solvent or of a mixture of organic solvents and (ii) 0-95 W/V % of water, (c) A 0.5-30 W/V % strength aqueous solution of a human serum protein and customary...

Full description

Saved in:
Bibliographic Details
Main Authors AHMED HEGASY, WOLFGANG HOEDERATH, HANS-JURGEN AHR, MANFRED WINTER, KLAUS BUHNER
Format Patent
LanguageEnglish
Published 28.07.1988
Edition4
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:Parenteral solutions comprising (a) a sparingly soluble medicament active compound, (b) a solvent consisting of (i) 5-100 M/V % of an organic solvent or of a mixture of organic solvents and (ii) 0-95 W/V % of water, (c) A 0.5-30 W/V % strength aqueous solution of a human serum protein and customary auxiliaries and/or excipients, 1 to 40,000 parts by weight, preferably 25 to 30,000 parts by weight of solvent (b) and 1 to 1,000,000 parts by weight, preferably 50 to 40,000 parts by weight, of human serum protein solution (c) being present per part by weight of medicament active compound. The sparingly soluble medicament active compounds which can be used have a solubility in water of between 1 mu g and 10 g, preferably between 10 mu g and 1 g per liter of water. Examples of such medicaments are dihydropyridine compounds and pyrazolones, and muzolimine.
Bibliography:Application Number: AU19880010323