TRIPEPTIDYL-ARGININALDEHYDE, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE ENTHALTENDE ARZNEIMITTEL SOWIE N-(MONOALKYL)- UND N,N-DI-(ALKYL)-XXX-LPROLIN-DIPEPTIDE

The invention relates to new peptide-aldehydes and a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same. According to a feature of the present invention there are provided new peptide-aldehyde derivatives corresponding to the general formula (I) (I) w...

Full description

Saved in:
Bibliographic Details
Main Authors HORVATH, GYULA, TOMORI GEB. JOSZT, EVA, FITTLER, ZSUZSA, JOZSA, FERENCZ, SZELL GEB. HASENOEHRL, ERZSEBET, BAGDY, DANIEL, BARABAS, EVA, DIOSZEGI, MARIANN, BAJUSZ, SANDOR
Format Patent
LanguageGerman
Published 15.10.1991
Edition5
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The invention relates to new peptide-aldehydes and a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same. According to a feature of the present invention there are provided new peptide-aldehyde derivatives corresponding to the general formula (I) (I) wherein R1 represents hydrogen or C1-6 alkyl group, R2 stands for C1-6 alkyl group, furthermore R1 and R2 are linked to the amino group of the Xxx alpha-amino acid, Xxx represents a D-phenylalanine residue or a D-alpha-amino acid group having in the side chain a C1-4 alkyl group, Pro stands for L-proline residue, Yyy stands for L-, D- or DL-arginine residue and A represents an acid residue. The new peptide-aldehyde derivatives of the invention possess valuable anticoagulant activity.
Bibliography:Application Number: AT19850116383T