BENZOXATHIIN-DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND PHARMAZEUTISCHE ZUSAMMENSTELLUNGEN

A benzoxathiin derivative having the formula wherein R represents hydrogen atom or a lower alkyl group, and R represents a lower alkyl group or an aralkyl group, or a pharmaceutically acceptable acid addition salt thereof Pharmaceutical compositions containing these compounds are extremely excellent...

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Bibliographic Details
Main Author HORI, MIKIO
Format Patent
LanguageEnglish
German
Published 15.12.1990
Edition5
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A benzoxathiin derivative having the formula wherein R represents hydrogen atom or a lower alkyl group, and R represents a lower alkyl group or an aralkyl group, or a pharmaceutically acceptable acid addition salt thereof Pharmaceutical compositions containing these compounds are extremely excellent as to anti-arrhythmic effect, while toxicity and side-effects are very low as compared to the conventional compounds, so that they can be used safely in the medical field, preferably as an ideal remedy for disorders of the cardiovascular system such as arrhythmia, angina pectoris, hypertension and the like. Said benzoxathiin derivative can be produced economically and effectively by reacting an intermediate compound having the general formula with an amine having the formula R R NH, wherein R and R have the same meanings as defined above.
Bibliography:Application Number: AT19850102644T