PYRAZINVERBINDUNGEN, IHRE VERWENDUNG UND HERSTELLUNGSVERFAHREN

The invention provides compounds according to formula (I) their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus...

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Bibliographic Details
Main Authors MAO, WANG, PROKOPOWICZ, ANTHONY, MORWICK, TINA
Format Patent
LanguageGerman
Published 15.08.2011
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Summary:The invention provides compounds according to formula (I) their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus useful for treating associated diseases and pathological conditions such as Pim kinase-mediated diseases and pathological conditions involving inflammation, including Chron's disease, inflammatory bowel disease, rheumatoid arthritis, and chronic inflammatory disease, or aberrant cell proliferation including various cancers.
Bibliography:Application Number: AT20070800116T