VERFAHREN ZUR BESTIMMUNG DER MENGE KONJUGIERTEN TAXANS IN POLYGLUTAMINSÄURE-TAXAN-KONJUGATEN

The invention relates to a method for determining the amount of conjugated taxane, in particular paclitaxel, in a PGA-taxane conjugate said method comprising: a) reacting the PGA-taxane conjugate with a compound formula (I): R 1 R 2 N-NH 2 (I) wherein R 1 and R 2 are as de...

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Bibliographic Details
Main Authors	FAZIONI, STEFANO, HOVDA, KEITH, SIVIERO, LUIGI, SPOONEMORE, HOLLY, LIVI, VALERIA, MCKENNON, MARC
Format	Patent
Language	German
Published	15.11.2010
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Summary:	The invention relates to a method for determining the amount of conjugated taxane, in particular paclitaxel, in a PGA-taxane conjugate said method comprising: a) reacting the PGA-taxane conjugate with a compound formula (I): R 1 R 2 N-NH 2 (I) wherein R 1 and R 2 are as defined in the description; to give a unbound taxane and a PGA hydrazide and b) determining the amount of unbound taxane.
Bibliography:	Application Number: AT20070004574T