CHINOLINDERIVATE, SYNTHESEVERFAHREN UND DIESE DERIVATE ENTHALTENDE MEDIKAMENTE
The invention relates to derivatives corresponding to formula I: in which X is an alkyl-(CH2)n- chain with n=0, 1 or 2, or O or N, Z is an aromatic which may contain heteroatoms chosen from O, N or S, as substitutions for the carbon atoms constituting said aromatic ring, this ring being substituted...
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Main Authors | , , , , , , , , , , |
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Format | Patent |
Language | German |
Published |
15.05.2009
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Subjects | |
Online Access | Get full text |
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Summary: | The invention relates to derivatives corresponding to formula I: in which X is an alkyl-(CH2)n- chain with n=0, 1 or 2, or O or N, Z is an aromatic which may contain heteroatoms chosen from O, N or S, as substitutions for the carbon atoms constituting said aromatic ring, this ring being substituted or otherwise with Rb, Rb represents 1 to 3 substituents chosen from -OH, -OR, -COOH, -COOR, -COH, -COR, -NH2, -NH(R), -NH(R,R'), -SH, -SR and CN, Ra is H or -(CH2)n'-Y, with n'=0, 1, 2 or 3 and Y and -CH3, -COOH, -COOR, -CN, -OH, -OR, SR, or an aryl group optionally substituted with Rb, R and R' represent a linear or branched alkyl chain of 1 to 4 C, and their pharmaceutically acceptable salts. Application as active ingredient of medicaments inhibiting retrovirus integrases. |
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Bibliography: | Application Number: AT20020795314T |