Z-OMEGA-THIO-SUBSTITUIERTE-2-(2,2DIMETHYLCYCLOPROPANCARBOXAMIDO)-2-ALKENSAEUREN, VERFAHREN ZU IHRER HERSTELLUNG UND DIESE ENTHALTENDE ZUSAMMENSETZUNG
Novel chemical compounds and a process for preparing them are provided. These compounds selectively inhibit the metabolism of dipeptidase (E.C.3.4.13.11) and therefore are useful in combination with antibacterial products. These chemical compounds are Z-2-(2,2-dimethylcyclopropanecarboxamido)- omega...
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Main Authors | , , , |
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Format | Patent |
Language | English German |
Published |
15.04.1989
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Edition | 4 |
Subjects | |
Online Access | Get full text |
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Summary: | Novel chemical compounds and a process for preparing them are provided. These compounds selectively inhibit the metabolism of dipeptidase (E.C.3.4.13.11) and therefore are useful in combination with antibacterial products. These chemical compounds are Z-2-(2,2-dimethylcyclopropanecarboxamido)- omega -pyridylthio-2-alkenoic acids (and related arylthio and heterocyclylthio analogs) of the general formula: wherein n is an integer from 3-5, Y is pyridyl, pyrimidinyl, tetrazolyl, imidazolyl, thiadiazolyl, thiazolinyl, or phenyl, optionally having 1 or 2 substituents which are hydroxyl, oxo, carboxyl, or methyl; and the loweralkyl (C1-6) esters and pharmaceutically acceptable salts thereof. |
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Bibliography: | Application Number: AT19810107303T |