VERFAHREN ZUR ISOLIERUNG VON PACLITAXEL

Paclitaxel is isolated by a process including normal phase chromatography using a polyamide stationary phase and a mixture containing a dialkyl ketone and a less polar solvent as a mobile phase. Suitable dialkyl ketones include acetone or methyl isobutyl ketone. Suitable less polar co-solvents inclu...

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Bibliographic Details
Main Authors SOBOTIK, ROMAN, CVAK, LADISLAV, BUCHTA, MARTIN, STVERKA, PAVEL
Format Patent
LanguageGerman
Published 15.10.2008
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Summary:Paclitaxel is isolated by a process including normal phase chromatography using a polyamide stationary phase and a mixture containing a dialkyl ketone and a less polar solvent as a mobile phase. Suitable dialkyl ketones include acetone or methyl isobutyl ketone. Suitable less polar co-solvents include a (C5-C8) aliphatic hydrocarbon, a (C6-C8) aromatic hydrocarbon, a (C1-C4) dialkyl ether or their mixtures.
Bibliography:Application Number: AT20050768158T