STABILE OXALIPLATIN ZUBEREITUNGEN

A storage stable pharmaceutical composition comprising a solution of Oxaliplatin in water and a catalytic amount of a carbohydrate. A process for forming such pharmaceutical composition comprising dissolving a known amount of Oxaliplatin in water; adding an amount of carbohydrate in the range of 0.0...

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Main Authors SINGH, AJEET KUMAR, JAIN, DEEPTI, MUKHARJEE, RAMA, PANANCHUKUNNATH, MANOJ KUMAR, BURMAN, ANAND C, PARSHOTAMDAS, DEEPAK JUDGELAL, UPADHYAY, SATISH CHANDRA
Format Patent
LanguageGerman
Published 15.08.2008
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Summary:A storage stable pharmaceutical composition comprising a solution of Oxaliplatin in water and a catalytic amount of a carbohydrate. A process for forming such pharmaceutical composition comprising dissolving a known amount of Oxaliplatin in water; adding an amount of carbohydrate in the range of 0.0010 % to 0.05% w/v with respect to such solution; agitating the mixture to get clear solution; filtering it through a filter membrane under aseptic conditions; and filling the solution resulting into glass vials sealed with elastomeric stoppers and aluminium flip-off seals.
Bibliography:Application Number: AT20060254598T