NEUE PYRIMIDIN-4,6-DICARBONS UREDIAMIDE ZUR SELEKTIVEN INHIBIERUNG VON KOLLAGENASEN

Pyrimidine-4,6-dicarboxamides of formula (I), are suitable for the selective inhibition of collagenase (MMP 13). The pyrimidine-4,6-dicarboxamides can thus be used for the treatment of degenerative joint diseases.

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Bibliographic Details
Main Authors KLINGLER, OTMAR, PIRARD, BERNARD, KIRSCH, REINHARD, WEITHMANN, KLAUS-ULRICH, ENGEL, CHRISTIAN, HABERMANN, JOERG
Format Patent
LanguageGerman
Published 15.03.2008
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Pyrimidine-4,6-dicarboxamides of formula (I), are suitable for the selective inhibition of collagenase (MMP 13). The pyrimidine-4,6-dicarboxamides can thus be used for the treatment of degenerative joint diseases.
Bibliography:Application Number: AT20030810401T