DEKONTAMINIERUNG MIT PRIONENINFIZIERTEM MATERIAL KONTAMINIERTER OBERFLÄCHEN MIT OXIDATIONSMITTELBASIERENDEN FORMULIERUNGEN

• Main Authors: SCOCOS, JENNIFER, KAISER, HERBERT, ANTLOGA, KATHLEEN, MCDONNELL, GERALD
• Format: Patent
• Language: German
• Published: 15.09.2007
• Subjects: AGRICULTURE; ANIMAL AND VEGETABLE OILS, FATS, FATTY SUBSTANCES AND WAXES; ANIMAL HUSBANDRY; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES; CANDLES; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES; CHEMISTRY; DETERGENT COMPOSITIONS; DETERGENTS; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; FATTY ACIDS THEREFROM; FISHING; FORESTRY; HUMAN NECESSITIES; HUNTING; HYGIENE; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES; MEDICAL OR VETERINARY SCIENCE; METALLURGY; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF; RECOVERY OF GLYCEROL; RESIN SOAPS; SOAP OR SOAP-MAKING; TRAPPING; USE OF SINGLE SUBSTANCES AS DETERGENTS

A surface which carries a material which is infected with prions is cleaned with an alkaline cleaning solution to remove as much proteinaceous material as possible from the surface. The cleaning agent is an alkaline cleaning agent which attacks prions remaining on the surface and which attacks prions removed from the surface during the cleaning step. After the cleaning solution is drained, a solution of surfactants, buffers, and heavy metal free corrosion inhibitors is circulated over the surface at 50°-60° C. The surfactants disperse and unclump the prion-contaminated material. A strong oxidant, preferably peracetic acid, is added to the solution to bring the peracetic acid concentration to 1,000-2,500 ppm. The peracetic acid or other strong oxidant attacks the prions, particularly the unclumped prion strands, deactivating the prions. After rinsing and drying, the surface may be wrapped in a microbe impermeable barrier and subjected to terminal sterilization, such as steam autoclaving.