PYRROLIDIN-DERIVATE ALS INHIBITOREN VON CYCLISCHER AMP-PHOSPHODIESTERASE

Novel pyrrolidine compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disord...

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Main Authors ODINGO, JOSHUA, MARTINS, TIMOTHY, J, BURGESS, LAURENCE, E, KESICKI, EDWARD, A, JONES, ZACHARY, S, NEWHOUSE, BRADLEY, J, FOWLER, KERRY, W, GAUDINO, JOHN, J, SCHLACHTER, STEPHEN, OLIVER, AMY
Format Patent
LanguageGerman
Published 15.06.2006
Edition7
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Summary:Novel pyrrolidine compounds that are potent and selective inhibitors of PDE4, as well as methods of making the same, are disclosed. Use of the compounds in the treatment of inflammatory diseases and other diseases involving elevated levels of cytokines, as well as central nervous system (CNS) disorders, also is disclosed.
Bibliography:Application Number: AT20000987999T