FUSIONSPROTEIN AUS HPV-L1 UND EINEM PEPTID, DAS EIN VLP BILDEN KANN UND ALS VEHIKEL ZUM EINSCHLEUSEN EINES PEPTIDS IN EINE ZELLE DIENEN KANN, SOWIE DESSEN MEDIZINISCHE VERWENDUNGEN

The invention relates to a carrier for introduction of a substance into cells, comprising a major capsid protein L1 of human papillomavirus (HPV-L1 protein) which has been intentionally modified to remove type-specific epitope(s) causing production of neutralising antibodies. The invention also incl...

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Bibliographic Details
Main Authors ANTONSSON, PER, KRISTENSSON, KARIN, DILLNER, JOAKIM, LANDO, PETER, WALLEN-OEHMAN, MARIE
Format Patent
LanguageGerman
Published 15.01.2006
Edition7
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
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Summary:The invention relates to a carrier for introduction of a substance into cells, comprising a major capsid protein L1 of human papillomavirus (HPV-L1 protein) which has been intentionally modified to remove type-specific epitope(s) causing production of neutralising antibodies. The invention also includes an oligo- or polynucleotide coding for said carrier, vaccines comprising said carrier or said oligo- or polynucleotide, as well as methods of using the carrier or the oligo- or polynucleotide in vaccination against infections of human papillomavirus, or against development of consequences of such an infection, or against development of certain cancers.
Bibliography:Application Number: AT20000966633T