CD45 INHIBITOREN

Substituted phenanthrene-9,10-diones in accord with structural diagram I, compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In compounds of the invention, R at each occurrence is independently...

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Bibliographic Details
Main Authors SYGOWSKI, LINDA, STEELMAN, GARY, URBANEK, REBECCA, KNAPPENBERGER, KATHERINE, SUCHARD, SUZANNE, VEALE, CHRIS, ALLAN, CHAPDELAINE, MARC, JEROME
Format Patent
LanguageGerman
Published 15.11.2005
Edition7
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Substituted phenanthrene-9,10-diones in accord with structural diagram I, compositions thereof and methods for the use thereof, for the treatment of T cell mediated conditions such as autoimmune diseases and organ graft rejection. In compounds of the invention, R at each occurrence is independently selected from hydrogen, halogen, NH-tosyl, N-di-tosyl, NH2, NO2, NH-CO-R , CO-NH-R , Ar, (CH2)nCH(COOH)R COR and NHCOCH2CH(COOH)NHR , where R , R and R are a selected from a variety of substituted or unsubstituted alkyl and aryl groupstand oligopeptides.
Bibliography:Application Number: AT20000985603T