2-ARACHIDONYLGLYCEROL, EIN HEMMER DES TUMOR NEKROSE FAKTORS -ALFA UND NEUROPROTEKTOR DES GEHIRNS BEI GESCHLOSSENEN KOPFVERLETZUNGEN

The present invention relates to 2-arachidonylglycerol (2-AG) to be used as inhibitor of a tumor necrosis factor (TNF-alpha), in the reduction of edema caused by closed head injury, in the reduction of neurological deficits caused by closed head injury and stroke and in treating pathological conditi...

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Bibliographic Details
Main Authors MECHOULAM, RAPHAEL, SHOHAMI, ESTHER, BREUER, AVIVA, GALLILY, RUTH, PANIKASHVILI, DAVID
Format Patent
LanguageGerman
Published 15.10.2004
Edition7
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention relates to 2-arachidonylglycerol (2-AG) to be used as inhibitor of a tumor necrosis factor (TNF-alpha), in the reduction of edema caused by closed head injury, in the reduction of neurological deficits caused by closed head injury and stroke and in treating pathological conditions caused by TNF-alpha and/or by radical oxygen intermediates (ROI), in pharmaceutical composition for the same use comprising as active ingredient 2-AG. It comprises also the use of 2-AG and pharmaceutical compositions comprising same in the preparation of a medicament for the treatment of said indications and methods of treatment by 2-AG and pharmaceutical compositions comprising same for diseases caused by said indications.
Bibliography:Application Number: AT20010943761T