VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON HALO-4-PHENOXYCHINOLINEN

The present invention relates to a new improved, simplified process for the preparation of halo-4-phenoxyquinolines, whereby thionyl chloride is used as the chlorinating agent to prepare the corresponding chloroquinoline intermediate prior to the final coupling reaction, and a single, inert high boi...

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Main Authors KRUMEL, KARL, L, HADD, MARK, A, ADAWAY, TIM, J, TAI, JIMMY, J, BUDD, JEFF, T, KING, IAN, R, OLMSTEAD, THOMAS, A, ROTH, GARY, A, KERSHNER, LARRY, D, MAURER, JULIE, L
Format Patent
LanguageGerman
Published 15.05.2003
Edition7
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Summary:The present invention relates to a new improved, simplified process for the preparation of halo-4-phenoxyquinolines, whereby thionyl chloride is used as the chlorinating agent to prepare the corresponding chloroquinoline intermediate prior to the final coupling reaction, and a single, inert high boiling polyether solvent is used throughout the entire reaction procedure.
Bibliography:Application Number: AT19980902547T