SUBSTITUIERTE HETEROCYCLISCHE BENZOCYCLOALKENE UND IHRE VERWENDUNG ALS ANALGETISCH WIRKSAME SUBSTANZEN

Aminomethyl substituted heterocyclic benzocycloalkene derivatives (I) are new. Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alky...

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Bibliographic Details
Main Authors PUETZ, CLAUDIA DR, STRASSBURGER, WOLFGANG DR, ZIMMER, OSWALD DR, ENGLBERGER, WERNER DR, KOEGEL, BABETTE-YVONNE DR
Format Patent
LanguageGerman
Published 15.12.2002
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:Aminomethyl substituted heterocyclic benzocycloalkene derivatives (I) are new. Aminomethyl substituted heterocyclic benzocycloalkene derivatives of formula (I) and their salts are new: R = OH; 1-6C alkoxy; or 3-7C cycloalkyloxy; R = 1-6C alkyl; R = 1-6C alkyl; aryl-1-2C alkyl; heterocyclyl-1-2C alkyl; -CH2-CH=C(R )2; or 3-7C cycloalkyl-methyl; R , R = H; Cl; F; CF3; 1-6C alkyl; OH; 1-6C alkoxy; 3-7C cycloalkyloxy; alpha , beta or beta , gamma -O-(CH2)o-O-; -(CH2)n-aryl; heterocyclyl; -O-(CH2)n-aryl; or alpha , beta - or beta , gamma -benzo optionally mono- or disubstituted by F, Cl, CF3, OH, 1-6C alkyl, 1-6C alkoxy or -CON(R R ); R = H or 1-6C alkyl; R = H; 1-6C alkyl; -(CH2)naryl; or CH2-3-7C cycloalkyl; or R + R = -(CH2)m or -(CH2)2-O-(CH2)2-; X = O; S; SO; or SO2; Y = -(CH2)0; -CH2-C(CH3)2-; or -C(CH3)2-; n = 0-2; m = 5-7; o = 1-2. An Independent claim is included for the preparation of compounds (I).
Bibliography:Application Number: AT19980122218T