NAPHTHYRIDINDERIVATE ALS ANGIOTENSIN-II- ANTAGONIST-INHIBITOREN

The invention concerns pharmaceutically useful compounds of the formula I, in which R , R , R , R , Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as...

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Bibliographic Details
Main Authors GIBSON, KEITH HOPKINSON, WOOD, ROBIN, RATCLIFFE, ARNOLD HARRY, PEARCE, ROBERT JAMES, MASEK, BRIAN BERNARD
Format Patent
LanguageGerman
Published 15.09.2001
Edition7
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The invention concerns pharmaceutically useful compounds of the formula I, in which R , R , R , R , Ra, Rb, A, X and Z have the various meanings defined herein, and their non-toxic salts, and pharmaceutical compositions containing them. The novel compounds are of value in treating conditions such as hypertension and congestive heart failure. The invention further concerns processes for the manufacture of the novel compounds and the use of the compounds in medical treatment.
Bibliography:Application Number: AT19920304791T