PIPERIDIN-DERIVATE UND DIESE ENTHALTENDE ANTIPLÄTTCHEN-AGENTS

Use of a piperidine derivative of general formula (I) or of a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use as a 5HT2 antagonist in the treatment of ischaemic disorder, thrombosis, obstruction, arteriosclerosis, migraine or microcirculation failure, or for anti-...

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Main Authors YOSHIMOTO, RYOTA, YAMAMOTO, HIROSHI, MAKINO, SHINGO, SHOJI, MASATAKA, ARISAKA, HARUMI
Format Patent
LanguageGerman
Published 15.09.2001
Edition7
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Summary:Use of a piperidine derivative of general formula (I) or of a pharmaceutically acceptable salt thereof in the manufacture of a medicament for use as a 5HT2 antagonist in the treatment of ischaemic disorder, thrombosis, obstruction, arteriosclerosis, migraine or microcirculation failure, or for anti-platelet treatment: wherein A represents an unsubstituted or substituted pyridyl, piperidyl, piperidino, morpholinyl, morpholino, thiomorpholinyl, thiomorpholino or piperazinyl group, a substituted alkyl group having 1 to 8 carbon atoms, a substituted cycloalkyl group having from 4 to 8 carbon atoms, or an unsubstituted or substituted alkoxy group having 1 to 8 carbon atoms, X represents a hydrogen atom or a halogen atom, Y represents one of the organic groups: -CONH-, -NHCO-, -CONHCH2-, -(CH2)n-, -COO-, wherein n is an integer of from 0 to 4, and Z represents one of the organic groups: -CH=CH-, -S-CH2-, -S-, -CH2-CH2-.
Bibliography:Application Number: AT19950302647T