VERFAHREN ZUR HERSTELLUNG VON POLYVALENTEN UND PHYSIOLOGISCH ABBAUBAREN KOHLENHYDRAT- REZEPTORBLOCKERN DURCH ENZYMATISCHE GLYCOSYLIERUNGSREAKTIONEN UND DEREN VERWENDUNG ZUR HERSTELLUNG VON KOHLENHYDRATBAUSTEINEN

The invention relates to a process for producing polyvalent polymer-based carbohydrate receptor blockers which in vivo do not, either in their complete form or when broken down, provoke intolerance reactions. The carbohydrate side chain of the receptor blocker is built up directly on the biodegradab...

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Bibliographic Details
Main Authors KRETZSCHMAR, GERHARD, BARTNIK, ECKART, SEIFFGE, DIRK, HOERSCH, BRIGITTE, AHLERS, MICHAEL
Format Patent
LanguageGerman
Published 15.09.1998
Edition6
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPIRITS
SUGARS
VINEGAR
WINE
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Summary:The invention relates to a process for producing polyvalent polymer-based carbohydrate receptor blockers which in vivo do not, either in their complete form or when broken down, provoke intolerance reactions. The carbohydrate side chain of the receptor blocker is built up directly on the biodegradable polymer by enzymatic glycolisation reactions in aqueous buffer systems and homogenous phase; the yields of these glycolisation reactions are considerably better than those of known processes, generally progress quantitatively and the accumulation densities are markedly increased. Also proposed is a process for producing free oligosaccharides using the carbohydrate receptor blockers produced according to the invention.
Bibliography:Application Number: AT19950923321T