NEUE CEPHALOSPORINANTIBIOTIKA UND VERFAHREN ZU IHRER HERSTELLUNG

Novel cephalosporin compounds of formula(I): wherein: R is a hydrogen or an amino protecting group; R and R are, independently, a hydrogen or a hydroxy protecting group, or form together a cyclic diol protecting group; R and R are, independently, a hydrogen or a carboxyl protecting group; X and Y ar...

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Main Authors LEE, TAE HEE, KIM, SE HO, YANG, DEOG HO, SEO, MI KYEONG, KIM, SAM SIK, KIM, YONG ZU, BANG, CHAN SIK, YEO, JAE HONG, LIM, JONG CHAN, WOO, YOUNG MIN, JEON, JAE HOON, OH, HUN SEUNG
Format Patent
LanguageGerman
Published 15.02.1998
Edition6
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Novel cephalosporin compounds of formula(I): wherein: R is a hydrogen or an amino protecting group; R and R are, independently, a hydrogen or a hydroxy protecting group, or form together a cyclic diol protecting group; R and R are, independently, a hydrogen or a carboxyl protecting group; X and Y are a nitrogen and a carbon atom, respectively, or a carbon and a nitrogen atom, respectively; R and R are, independently, a hydrogen or an amino, substituted amino, hydroxy, alkoxy, C1-4 alkyl, carboxyl or alkoxy carbonyl group, or jointly form a C3-7 cycloalkyl group together with the carbon to which they are attached, when X and Y are a nitrogen and a carbon, respectively, or R is a hydrogen or an amino group when X and Y are a carbon and a nitrogen, respectively; and Q is =CH- or =N-, or pharmaceutically acceptable non-toxic salts, physiologically hydrolyzable esters, hydrates and solvates and isomers thereof, and isomers thereof possess potent and broad antibacterial activities.
Bibliography:Application Number: AT19940114226T