VERWENDUNG VON TRICLOSAN ZUR HERSTELLUNG EINES ARZNEIMITTELS ZUR INHIBIERUNG DER CYCLOOXYGENASE

The present invention relates to the prevention of periodontitis by the use of a medicament which contains Triclosan. It has been found that Triclosan has a considerable anti-cyclo-oxygenase activity, thus inhibiting the formation of prostaglandins which are mediators of the loss of alveolar bone in...

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Main Authors HULL, DEREK MICHAEL C., UNILEVER RESEA, VAN DER OUDERAA, FRANCISCUS J., UNILEV, CUMMINS, DIANE, UNILEVER RESEARCH, ROAD EAST, BEBINGTON, BEBINGTON
Format Patent
LanguageGerman
Published 15.04.1996
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:The present invention relates to the prevention of periodontitis by the use of a medicament which contains Triclosan. It has been found that Triclosan has a considerable anti-cyclo-oxygenase activity, thus inhibiting the formation of prostaglandins which are mediators of the loss of alveolar bone in the periodontium. Reducing the formation of said prostaglandins therefore reduces said loss of alveolar bone, which is one of the symptoms connected with periodontitis. The medicament is preferably in the form of a toothpaste.
Bibliography:Application Number: AT19920202287T