NIEDRIG SCHMELZBARER, GIESSBARER ARZNEIMITTEL- EXCIPIENT UND SEINE VERWENDUNG IM ZUSAMMENHANG MIT PHARMAZEUTISCHEN ZUSAMMENSETZUNGEN

An exicipient for a pharmaceutical compound which melts at body temperature but will not spontaneously deform at higher temperatures encountered in shipment and storage comprises: -Low MW Polyethylene glycol 75-90% -(M.P. about 37 DEG C.) -Medium to high MW polyethylene glycol 0-4% -Long chain satur...

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Bibliographic Details
Main Author SNIPES, WALLACE, C
Format Patent
LanguageGerman
Published 15.03.1995
Edition6
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:An exicipient for a pharmaceutical compound which melts at body temperature but will not spontaneously deform at higher temperatures encountered in shipment and storage comprises: -Low MW Polyethylene glycol 75-90% -(M.P. about 37 DEG C.) -Medium to high MW polyethylene glycol 0-4% -Long chain saturated carboxylic acid 0-4% -Polyethylene oxide 0-4% -(MW 100,000-5,000,000) -Colloidal silica 10-20%. - The excipient is particularly advantageous for the preparation of dosage forms for buccal administration of pharmaceutical compounds.
Bibliography:Application Number: AT19890911956T