BETA-LACTAMVERBINDUNGEN UND DEREN HERSTELLUNG

Described are amino acid compounds of the formula: wherein R is a lower alkyl group, R1 is a hydrogen atom or a protecting group for carboxyl, R2 is a hydrogen atom, a protecting group for amino, an optionally substituted allyl group of the formula: (wherein R3 and R4 are each a hydrogen atom, a low...

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Main Authors SASAKI, AKIRA SUMITOMO PHARMACEUTICALS, MATSUMURA, HARUKI SUMITOMO PHARMACEUTI, KASUGADENAKA 3OME KONOHANA-KU, SUNAGAWA, MAKOTO SUMITOMO PHARMACEUTIC, CHOME KONOHANA-KU, NOZAKI, YOSHIHITO SUMITOMO PHARMACEUTI
Format Patent
LanguageGerman
Published 15.08.1994
Edition5
Subjects
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Described are amino acid compounds of the formula: wherein R is a lower alkyl group, R1 is a hydrogen atom or a protecting group for carboxyl, R2 is a hydrogen atom, a protecting group for amino, an optionally substituted allyl group of the formula: (wherein R3 and R4 are each a hydrogen atom, a lower alkyl group or an aryl group), a beta-hydroxyethyl group in which the hydroxyl group is optionally protected, a formylmethyl group in which the formyl group is optionally protected, a carboxymethyl group in which the carboxyl group is protected or a 2-furylmethyl group and X is an optionally protected carboxyl group, a hydroxymethyl group in which the hydroxyl group is optionally protected or a substituted mercaptomethyl group of the formula: -CH2SR5 (wherein R5 is an aryl group or an ar(lower)alkyl group), which are useful intermediates in the synthesis of 1-alkylcarbapenem compounds.
Bibliography:Application Number: AT19860117997T