AGENTES DE UNIÓN A C3 Y MÉTODO DE USO DE LOS MISMOS

• Main Authors: LIU, ZHONGHAO, HIGBEE, JARED MARTIN, ZHAI, WENWU, YIN, YIYUAN, TANG, JIE, WANG, YAN, DUEY, DANA YEN MEI
• Format: Patent
• Language: Spanish
• Published: 18.08.2021
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; ORGANIC CHEMISTRY; PEPTIDES; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; SPIRITS; VINEGAR; WINE

La presente divulgación proporciona agentes de unión, como por ej, anticuerpos (que incluyen los fragmentos variables de cadena simple), que se unen específicamente al componente complemento C3, que incluyen el C3 humano, las composiciones que comprenden los mismos, y los métodos para su uso. La divulgación, además, proporciona polinucleótidos y vectores relacionados que codifican los agentes de unión y las células que comprenden a estos. The present disclosure provides binding agents, such as antibodies (including single chain variable fragments), that specifically bind complement component C3, including human C3, compositions comprising same, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising same.