TABLETA A PRUEBA DE ALTERACION QUE PROPORCIONA LIBERACION INMEDIATA DEL FARMACO

• Main Authors: SCHWIER SEBASTIAN, HAUPTS MARCEL, RTTGERS UDO, BARNSCHEID LUTZ, PTZ JANA
• Format: Patent
• Language: Spanish
• Published: 19.03.2014
• Subjects: HUMAN NECESSITIES; HYGIENE; MEDICAL OR VETERINARY SCIENCE; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS

La presente se refiere a una tableta a prueba de alteración comprendiendo (i) un material matriz en una cantidad de más de un tercio del peso total de la tableta; y (ii) una pluralidad de material particulado en una cantidad de menos de dos tercios del peso total de la tableta; en donde el material particulado comprende un compuesto farmacológicamente activo y un óxido de polialquileno; y forma una fase discontinúa dentro del material matriz. The invention relates to a tamper-resistant tablet comprising (i) a matrix material in an amount of more than one third of the total weight of the tablet; and (ii) a plurality of particulates in an amount of less than two thirds of the total weight of the tablet; wherein said particulates comprise a pharmacologically active compound and a polyalkylene oxide; and form a discontinuous phase within the matrix material; and method of using said tablet to treat pain and other conditions.