Macrocyclic compounds as inhibitors of viral replication

The embodiments provide macrocylic compounds, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of tre...

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Main Authors JIANG YUTONG, WENGLOWSKY, STEVEN, M, CONDROSKI, KEVIN, R, JOSEY JOHN ANTHONY, STENGEL PETER JOHN, BLATT, LAWRENCE, M, DOHERTY GEORGE ANDREW, ANDREWS STEVEN WADE, KENNEDY APRIL LAYNE, MADDURU, MACHENDER, R
Format Patent
LanguageEnglish
Published 31.10.2006
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The embodiments provide macrocylic compounds, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating flaviviral infection, including hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition.
Bibliography:Application Number: AP20060003763