Swelling behavior of cross-link PVA with glutaraldehyde
The polymeric hydrogels composed of poly vinyl alcohol (m.wt 72000) and glutaraldehyde (5 %,8 % and 10 %), have been thermally prepared for the purpose of studying their swelling and drug release behavior . The swelling ratio was measured for all the hydrogel samples at 37°C, in three different medi...
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Published in | Ibn Al-Haitham Journal for Pure and Applied Sciences Vol. 28; no. 2; pp. 136 - 146 |
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Main Authors | , , |
Format | Journal Article |
Language | Arabic English |
Published |
بغداد، العراق
جامعة بغداد، كلية التربية ابن الهيثم
2015
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Subjects | |
Online Access | Get full text |
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Summary: | The polymeric hydrogels composed of poly vinyl alcohol (m.wt 72000) and glutaraldehyde (5 %,8 % and 10 %), have been thermally prepared for the purpose of studying their swelling and drug release behavior .
The swelling ratio was measured for all the hydrogel samples at 37°C, in three different media pH (1.2, 4.7 and 6.8) as a function of time. The results show that the maximum swelling ratios were arranged as follows : pH = 6.8 > pH = 4.7 > pH = 1.2 hydrogels cross linked PVA showed a typical pH responsive behavior such as high pH has maximum swelling while low pH shows minimum swelling. |
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ISSN: | 1609-4042 2521-3407 |