Synthesis of 2 H-pyrroles via the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides

3,4-Dihydro-2 H-pyrrole derivatives were synthesized by the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides. Acrylamide substitution patterns and benzimidoyl chloride equilibration were investigated.

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Bibliographic Details
Published inTetrahedron letters Vol. 47; no. 4; pp. 477 - 481
Main Authors Yoo, Choong Leol, Olmstead, Marilyn M., Tantillo, Dean J., Kurth, Mark J.
Format Journal Article
LanguageEnglish
Published Elsevier Ltd 2006
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Summary:3,4-Dihydro-2 H-pyrrole derivatives were synthesized by the 1,3-dipolar cycloaddition reaction of nitrile ylides with acrylamides. Acrylamide substitution patterns and benzimidoyl chloride equilibration were investigated.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2005.11.066