ULTRASOUND FINDINGS IN SALIVARY GLANDS AND ASSOCIATIONS IN PRIMARY SJOGREN´S SYNDROME AND SICCA NON-SJOGREN PATIENTS

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 137; no. 6; pp. e294 - e295
• Main Authors: GOMES, Lucas Tadeu Ferreira, FELIX, Fernanda Aragão, CALDERARO, Débora Cerqueira, TANURE, Leandro Augusto, de CASTRO, Maurício Augusto Aquino, da SILVA, Tarcília Aparecida, SOUSA, Sílvia Ferreira DE
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.06.2024
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.12.686

To associate clinicopathological findings with ultrasonographic (US) features of major salivary glands in patients with primary Sjogren´s syndrome (pSS) and sicca non-Sjogren (snS). A pilot study was conducted on eight patients with pSS and ten with snS. US evaluation was performed using the OMERACT gray-scale and vascularity scoring system. Clinicopathological data were compared between the two groups. Gray-scale US findings showed significant differences between pSS and snS patients (p<0.05), with higher grades scoring in the pSS group. Doppler mode revealed differences in vascularity between the groups (p<0.05). Moderate and severe US abnormalities were associated with a positive focus score and anti-SSA/Ro (p<0.05). Only the right parotid gland did not show differences between both groups (p>0.05). The other clinicopathological parameters evaluated (sex, hyposalivation, and anti-SSB/Lo) did not show an association with US findings (p>0.05). Higher grades of abnormalities and vascularization were found in pSS patients and positively associated with focus score and anti-SSA/Ro. Despite being preliminary, the data could favor US as a complementary diagnostic test for pSS diagnosis. Funding: CAPES; FAPEMIG