ODONTOGENIC KERATOCYSTS ASSOCIATED WITH GORLIN GOLTZ SYNDROME WITH CBCT IMAGES IN AN ELDERLY PATIENT: A 7-YEAR FOLLOW-UP

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 137; no. 6; p. e233
• Main Authors: COUTO, Douglas Augusto Fernandes, GRIGOLO, Daniel, MACEDO, Nayara Flores, BAGGIO, Gabriela Leite, CORRÊA, Emilly Godinho, BISINELLI, Julio César, AZEVEDO-ALANIS, Luciana Reis
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.06.2024
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.12.414

In 2017, a 56-year-old man was referred to a dental clinic due to a maxillary toothache. A panoramic radiograph incidentally revealed three well-defined circular radiolucent images in the right posterior region of the mandibular body and ramus. Further details were obtained through cone-beam computed tomography. Since surgical access was challenging, biopsies were performed on two of the lesions. Microscopic examination confirmed features consistent with odontogenic keratocyst. The ultimate diagnosis of Gorlin Goltz syndrome was confirmed due to the presence of frontal bossing, palmar and plantar pits, along with abnormalities detected in a chest X-ray. The biopsied lesions showed significant improvement following enucleation and marsupialization treatment. In 2023, during a radiographic follow-up, it was determined that the third lesion had become more accessible, and the same therapy was applied. Over the course of a 7-year follow-up, the bone healing of these lesions demonstrated excellent results. We remain vigilant regarding potential predispositions of the syndrome, particularly those with malignant potential.