CLINICOPATHOLOGICAL FEATURES OF SUBGEMMAL NEUROGENOUS PLAQUE: REPORT OF 4 CASES

• Published in: Oral surgery, oral medicine, oral pathology and oral radiology Vol. 137; no. 6; p. e207
• Main Authors: SOUSA, Julliany Taverny, MORAIS, Hannah Gil de Farias, COLARES, Débora Frota, GONÇALO, Rani Iani Costa, da SILVEIRA, Éricka Janine Dantas, QUEIROZ, Lélia Maria Guedes
• Format: Journal Article
• Language: English
• Published: Elsevier Inc 01.06.2024
• ISSN: 2212-4403; 2212-4411
• DOI: 10.1016/j.oooo.2023.12.293

Four cases of subgemmal neurogenous plaque (SNP) are reported here, detailing their clinical presentation, histopathological features, and treatment outcomes. These cases exhibited a predilection for females, with an average age of 49.5 years. Clinically, the lesions presented as nodules or papules of varying colors, spanning from normochromic to erythematous or yellowish, and measuring between 0.5 to 2 cm. Patients reported painful symptoms, with some describing burning or tingling sensations, and no identifiable etiological factors were noted. Following excisional biopsy, the histopathological diagnosis was confirmed by the presence of fusiform cells, which were at times wavy or virguliform, organized in plexuses or dispersed within the connective tissue. In some cases, taste buds, inflammatory cells, and lymphoid tissue were observed. During follow-up, patients reported improvement in pain symptoms and no recurrence. SNP is a structure typically found on the tongue, with a higher prevalence in women over 40 years of age, and it is associated with painful symptoms. Therefore, it is crucial for clinicians and pathologists to be aware of SNP to avoid misdiagnosis.